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Metabolic Health

Understanding PCOS: A Metabolic Disorder at Its Root

May 30, 2025

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By: Weight Loss NP, LLC

Polycystic Ovarian Syndrome (PCOS) is one of the most common hormonal disorders affecting women of reproductive age. While it’s often discussed in the context of irregular periods or fertility struggles, at its core, PCOS is a metabolic disorder.

What is PCOS?

PCOS is a condition in which the ovaries produce an abnormal amount of androgens, male sex hormones that are usually present in small amounts in women. This causes and imbalance of rest of the woman’s reproductive hormones and leads to oftentimes troublesome symptoms. PCOS gets its name from the numerous small cysts (fluid-filled sacs) that may form on the ovaries, although not all women with PCOS have cysts.

The Role of Insulin Resistance in PCOS

One of the key drivers of PCOS is insulin resistance. This means that the body’s cells don’t respond properly to insulin, making it harder to keep blood sugar levels stable. As a result, the pancreas produces more insulin to compensate. Elevated insulin levels can lead to increased androgen production, which in turn worsens PCOS symptoms like acne, hair growth, and irregular cycles.

Insulin resistance and PCOS is also closely linked to weight gain, especially around the abdominal area. Unfortunately, excess weight can make PCOS symptoms more severe, creating a frustrating cycle for many women.

Symptoms of PCOS

PCOS symptoms can vary from woman to woman, but the most common include:

  • Irregular or missed periods
  • Excess facial or body hair (hirsutism)
  • Acne or oily skin
  • Thinning hair or hair loss on the scalp
  • Weight gain or difficulty losing weight
  • Darkening of the skin, particularly around the neck or underarms
  • Mood changes or depression
  • Infertility or trouble getting pregnant

Weight Loss and PCOS

The good news is that weight loss can significantly improve PCOS symptoms. Even a modest reduction in body weight (5-10%) can help regulate periods, improve insulin sensitivity, and increase the chances of ovulation and pregnancy.

At Weight Loss NP, we specialize in helping women with PCOS lose weight in a sustainable, positive, and medically-guided way. Our focus on metabolism and hormone balance makes us uniquely equipped to support women facing this condition.

Treatment Options: GLP-1 Medications and Metformin

Two medications often used in the treatment of PCOS-related insulin resistance include:

GLP-1 medications (like semaglutide and tirzepatide): Originally developed for diabetes, these medications improve insulin sensitivity, reduce appetite, and support weight loss. Many women with PCOS see improvement in their cycles, energy, and fertility while using GLP-1 medications.

Metformin: This oral medication improves insulin resistance and helps regulate menstrual cycles in many women with PCOS. It may also help with weight management, although its effects are typically more modest than GLP-1 medications.

Improving Fertility and Breaking the Vicious Cycle: Treating PCOS

By addressing the metabolic root of PCOS and reducing insulin resistance, many women experience improved fertility and feel much better overall. Whether your goal is to regulate your periods, reduce hormonal symptoms, increase your energy, or get pregnant, managing insulin and metabolism is key.

Final Thoughts

PCOS is more than just a reproductive issue—it’s a complex metabolic condition that requires a comprehensive approach. At Weight Loss NP, we’re here to help you take control of your health, your hormones, and your future!

Ready to get started? Book your consultation today and take the first step toward feeling better and living well.

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